Comments on: Prakriti-Based Differences in Drug Response: Pharmacogenomic Evidence from Indian Clinical Trials https://www.ayurvedhealing.com/prakriti-drug-response-differences-pharmacogenomic-indian-trials/ Ancient Wisdom for Modern Wellness Sun, 13 Sep 2026 08:00:18 +0000 hourly 1 https://wordpress.org/?v=7.0.2 By: Karthik Gupta https://www.ayurvedhealing.com/prakriti-drug-response-differences-pharmacogenomic-indian-trials/#comment-89323 Sun, 13 Sep 2026 08:00:18 +0000 https://www.ayurvedhealing.com/?p=3391#comment-89323 correlating a traditional constitutional type with genomic data is methpdologically fraught. the article is too optimistic. tbh

]]> By: Steve Anderson https://www.ayurvedhealing.com/prakriti-drug-response-differences-pharmacogenomic-indian-trials/#comment-89269 Fri, 28 Aug 2026 21:21:44 +0000 https://www.ayurvedhealing.com/?p=3391#comment-89269 how far are we from Prakriri-based prescribing in actual clinical practice? seems like a long validation pathway.

]]> By: Emily Foster https://www.ayurvedhealing.com/prakriti-drug-response-differences-pharmacogenomic-indian-trials/#comment-686099 Fri, 21 Aug 2026 16:41:16 +0000 https://www.ayurvedhealing.com/?p=3391#comment-686099 Future research that integrates physiological measurements with questionnaire data might improve the objectivity of prakriti assessment.

]]> By: Rekha Sinha https://www.ayurvedhealing.com/prakriti-drug-response-differences-pharmacogenomic-indian-trials/#comment-89175 Fri, 21 Aug 2026 11:38:16 +0000 https://www.ayurvedhealing.com/?p=3391#comment-89175 @Linda the pharmacogenomic angle on Prakriti is genuinely novel. the Vata-Pitta difference in CYP2C19 expression being correlated with clinical outcome is striking.

]]> By: Sandeep Joshi https://www.ayurvedhealing.com/prakriti-drug-response-differences-pharmacogenomic-indian-trials/#comment-89147 Wed, 19 Aug 2026 14:42:00 +0000 https://www.ayurvedhealing.com/?p=3391#comment-89147 In reply to Christopher Wilson.

@Christopher as a researcher I found the Chennai AIIMS trial data particularly relevant. sample sizes are small but the direction is consistent.

]]> By: Jessica Reed https://www.ayurvedhealing.com/prakriti-drug-response-differences-pharmacogenomic-indian-trials/#comment-686098 Wed, 19 Aug 2026 09:18:17 +0000 https://www.ayurvedhealing.com/?p=3391#comment-686098 The idea of using prakriti as a low cost proxy for pharmacogenomic profiling could be valuable in primary care settings where genotyping is scarce.

]]> By: Christopher Wilson https://www.ayurvedhealing.com/prakriti-drug-response-differences-pharmacogenomic-indian-trials/#comment-89144 Tue, 18 Aug 2026 22:42:23 +0000 https://www.ayurvedhealing.com/?p=3391#comment-89144 the pharmacogenomic angle on Prakriti is genuinely novek. the Vata-Pitta difference in CYP2C19 expression being correlated with clinical outcome is striking.

]]> By: Mark Bennett https://www.ayurvedhealing.com/prakriti-drug-response-differences-pharmacogenomic-indian-trials/#comment-686097 Mon, 17 Aug 2026 12:38:06 +0000 https://www.ayurvedhealing.com/?p=3391#comment-686097 I appreciate the proposed framework that outlines monitoring priorities for each prakriti type, like watching for neurological side effects in vata individuals.

]]> By: Rebecca Shah https://www.ayurvedhealing.com/prakriti-drug-response-differences-pharmacogenomic-indian-trials/#comment-89128 Sun, 16 Aug 2026 15:25:41 +0000 https://www.ayurvedhealing.com/?p=3391#comment-89128 ]]> @Geeta the article mentions Pitta Prakriti correlating with faster drug metabolism. does this mean Pitta types need higher doses of certain medications? 🌿

]]> By: Kevin Martin https://www.ayurvedhealing.com/prakriti-drug-response-differences-pharmacogenomic-indian-trials/#comment-686096 Sat, 15 Aug 2026 09:26:15 +0000 https://www.ayurvedhealing.com/?p=3391#comment-686096 It’s interesting that HLA DRB1 associations were mentioned, linking immune response differences to prakriti classification beyond just metabolism.

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